Biomarkers and clinical sample data
We screen and assess biomarkers using clinical sample data, and map the results back to mechanism and clinical context.
SERVICE 04
Preclinical and Translational Research Support
Biomarkers, clinical sample data and antibody drug strategy; in vivo and in vitro study design. Target assessment, sample size, manuscript support.
When you need this
- A study is about to start and the protocol and sample size aren't settled.
- In vivo and in vitro results don't agree, and you need to know whether the problem is in the design or the analysis.
- The program is moving toward the clinic and needs a biomarker strategy.
- An antibody program needs a data-based assessment of the target and strategy.
- A manuscript is ready to submit and someone needs to own the analysis.
METHODS
What we do
Antibody drug strategy
A data-based assessment of the target to inform strategic decisions in antibody programs.
Study design and interpretation
Design and interpretation of in vivo and in vitro studies, including sample size calculated before the study starts, not after.
Manuscript support
Support with methods, figures and results sections.
DELIVERABLES
Deliverables
- Target assessment report
- Study protocol and sample size
- Manuscript support
QUESTIONS WE HEAR
Questions R&D teams bring us
"How many animals per group do we need in the next study to have enough statistical power?"
"Our in vitro and in vivo results point in different directions. Is it the study design or the analysis?"
"This antibody program is heading to the clinic. How should we choose and validate biomarkers?"
Start with one question
Tell us where the program stands and what decision comes next. In a free 30-minute consultation, we'll tell you where we can help.